Longevity &
Preventative Care

Extending HealthSpan Through Precision, Prevention, and Proactive Care

Longevity medicine isn’t about living longer at any cost—it’s about living better, longer. At HealthSpan Internal Medicine, Dr. Jessica Knape focuses on extending healthspan: the years you remain cognitively sharp, physically strong, metabolically healthy, and independent.

This approach blends traditional internal medicine with advanced diagnostics, clinical genomics, metabolomics, and lifestyle medicine to identify risks early and intervene before disease takes hold.

A Medicine 3.0 Approach to Prevention

Conventional medicine often waits for disease to declare itself. Longevity medicine at HealthSpan is proactive, data-driven, and individualized.

Dr. Knape evaluates:

  • Metabolic and cardiovascular risk

  • Inflammatory burden

  • Hormonal balance

  • Cognitive resilience

  • Sleep quality and recovery

  • Body composition and muscle health

  • Genetic risk patterns

The goal is early detection, targeted intervention, and sustained optimization across every major system.

Advanced Testing for Longevity Optimization

Preventive care at HealthSpan may include:

  • Advanced metabolic and cardiovascular testing

  • Coronary artery imaging and vascular risk assessment (including Cleerly and other advanced cardiac tools)

  • Clinical genomics (IntellxxDNA®) to personalize prevention strategies

  • Metabolomics and nutrient analysis

  • Hormone and thyroid evaluation

  • Cognitive risk screening

These tools allow Dr. Knape to move beyond population averages and create a plan tailored to your biology.

Interventions Designed to Preserve Function

Longevity care is not a protocol—it’s a living plan that evolves with you. Interventions may include:

  • Precision nutrition and metabolic optimization

  • Hormone optimization when appropriate

  • Targeted supplementation based on lab data

  • Peptide therapy to support repair, resilience, and recovery

  • Exercise guidance focused on muscle preservation and mitochondrial health

  • Sleep and stress optimization strategies

The emphasis is always on function, safety, and sustainability.

Protecting the Brain, Heart & Metabolism

The strongest predictors of long-term healthspan are metabolic health, cardiovascular integrity, and cognitive resilience. Dr. Knape’s longevity model integrates all three—recognizing that brain health, heart health, and metabolism are deeply interconnected.

This approach is especially valuable for patients with:

  • Family history of dementia or heart disease

  • Midlife metabolic changes

  • Early cardiovascular risk markers

  • Cognitive concerns or brain fog

  • A desire to stay active and independent with age

Conditions and Risks Commonly Addressed

  • Cardiovascular Disease Prevention

  • Cognitive Decline Risk

  • Metabolic Syndrome and Insulin Resistance

  • Hormonal Decline with Aging

  • Osteopenia and Bone Health

  • Inflammation and Accelerated Aging

  • Fatigue and Reduced Recovery

  • Genetic Risk for Chronic Disease

A Thoughtful, Physician-Led Model of Longevity Care

Longevity medicine at HealthSpan is:

  • Led by a board-certified internal medicine physician

  • Grounded in evidence and advanced diagnostics

  • Personalized—not algorithmic

  • Focused on prevention, resilience, and independence

This is care for people who want to understand their health deeply and invest in long-term vitality.

If you want a proactive, precision-based approach to aging well—before problems arise—longevity and preventive medicine at HealthSpan can help.

Ready to Invest in Your HealthSpan?

to explore personalized longevity care with Dr. Knape.